increased circulating total protein level_Col4a3<tm1Dec>/Col4a3<tm1Dec>,Itga1<tm1Gdnr>/Itga1<tm1Gdnr>

http://metadb.riken.jp/0005568I129S4SvJae129X1SvJBALBcCol4a3tm1DecCol4a3tm1DecItga1tm1GdnrItga1tm1GdnrCol4a3tm1DecItga1tm1Gdnr

increased circulating total protein level_Col4a3<tm1Dec>/Col4a3<tm1Dec>,Itga1<tm1Gdnr>/Itga1<tm1Gdnr>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• integrin alpha 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:96599
• collagen, type IV, alpha 3
  http://metadb.riken.jp/db/mgi_rdf/MGI:104688

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Col4a3<tm1Dec>/Col4a3<tm1Dec>,Itga1<tm1Gdnr>/Itga1<tm1Gdnr>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Col4a3<tm1Dec>|Itga1<tm1Gdnr>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S4/SvJae * 129X1/SvJ * BALB/c

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased circulating total protein level
  http://purl.obolibrary.org/obo/MP_0005568

文献

http://purl.org/net/cito/citesAsAuthority

• D. Cosgrove, et.al., Integrin alpha1beta1 and transforming growth factor-beta1 play distinct roles in alport glomerular pathogenesis and serve as dual targets for metabolic therapy., The American journal of pathology, 2000, 157
  http://rdf.ncbi.nlm.nih.gov/pubmed/11073824