abnormal enzyme/coenzyme activity_Lepr<db>/Lepr<db>,Serpine1<tm1Mlg>/Serpine1<tm1Mlg>

http://metadb.riken.jp/0005584I129S2SvPasC57BL6C57BLKSJLeprdbLeprdbSerpine1tm1MlgSerpine1tm1MlgSerpine1tm1MlgLeprdb

abnormal enzyme/coenzyme activity_Lepr<db>/Lepr<db>,Serpine1<tm1Mlg>/Serpine1<tm1Mlg>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• leptin receptor
  http://metadb.riken.jp/db/mgi_rdf/MGI:104993
• serine (or cysteine) peptidase inhibitor, clade E, member 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:97608

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Lepr<db>/Lepr<db>,Serpine1<tm1Mlg>/Serpine1<tm1Mlg>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Serpine1<tm1Mlg>|Lepr<db>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S2/SvPas * C57BL/6 * C57BLKS/J

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal enzyme/coenzyme activity
  http://purl.obolibrary.org/obo/MP_0005584

文献

http://purl.org/net/cito/citesAsAuthority

• Sarah J. Collins, et.al., Plasminogen activator inhibitor-1 deficiency has renal benefits but some adverse systemic consequences in diabetic mice., Nephron. Experimental nephrology, 2006, 104
  http://rdf.ncbi.nlm.nih.gov/pubmed/16735799