decreased vasodilation_Gucy1b3<tm1.2Frb>/Gucy1b3<tm1.2Frb>,X/Tg(Myh11-cre/ERT2)1Soff

http://metadb.riken.jp/0005591B6CgGucy1b3tm12FrbTgMyh11creERT21SoffGucy1b3tm12FrbGucy1b3tm12FrbXTgMyh11creERT21SoffTgMyh11creERT21SoffGucy1b3tm12Frb

decreased vasodilation_Gucy1b3<tm1.2Frb>/Gucy1b3<tm1.2Frb>,X/Tg(Myh11-cre/ERT2)1Soff

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 1, Stefan Offermanns
  http://metadb.riken.jp/db/mgi_rdf/MGI:3819268
• guanylate cyclase 1, soluble, beta 3
  http://metadb.riken.jp/db/mgi_rdf/MGI:1860604

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Gucy1b3<tm1.2Frb>/Gucy1b3<tm1.2Frb>,X/Tg(Myh11-cre/ERT2)1Soff

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Myh11-cre/ERT2)1Soff|Gucy1b3<tm1.2Frb>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• B6.Cg-Gucy1b3<tm1.2Frb> Tg(Myh11-cre/ERT2)1Soff

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased vasodilation
  http://purl.obolibrary.org/obo/MP_0005591

文献

http://purl.org/net/cito/citesAsAuthority

• Dieter. Groneberg, et.al., Smooth muscle-specific deletion of nitric oxide-sensitive guanylyl cyclase is sufficient to induce hypertension in mice., Circulation, 2010, 121
  http://rdf.ncbi.nlm.nih.gov/pubmed/20065162