abnormal vascular smooth muscle physiology_Apoe<tm1Unc>/Apoe<tm1Unc>,Cdkn1a<tm1Tyj>/Cdkn1a<tm1Tyj>

http://metadb.riken.jp/0005595B6129Apoetm1UncCdkn1atm1TyjApoetm1UncApoetm1UncCdkn1atm1TyjCdkn1atm1TyjCdkn1atm1TyjApoetm1Unc

abnormal vascular smooth muscle physiology_Apoe<tm1Unc>/Apoe<tm1Unc>,Cdkn1a<tm1Tyj>/Cdkn1a<tm1Tyj>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• cyclin-dependent kinase inhibitor 1A (P21)
  http://metadb.riken.jp/db/mgi_rdf/MGI:104556
• apolipoprotein E
  http://metadb.riken.jp/db/mgi_rdf/MGI:88057

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Apoe<tm1Unc>/Apoe<tm1Unc>,Cdkn1a<tm1Tyj>/Cdkn1a<tm1Tyj>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Cdkn1a<tm1Tyj>|Apoe<tm1Unc>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• B6.129-Apoe<tm1Unc> Cdkn1a<tm1Tyj>

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal vascular smooth muscle physiology
  http://purl.obolibrary.org/obo/MP_0005595

文献

http://purl.org/net/cito/citesAsAuthority

• Takeshige. Kunieda, et.al., Angiotensin II induces premature senescence of vascular smooth muscle cells and accelerates the development of atherosclerosis via a p21-dependent pathway., Circulation, 2006, 114
  http://rdf.ncbi.nlm.nih.gov/pubmed/16908765