increased susceptibility to type I hypersensitivity reaction_Mir21a<tm1.1Mer>/Mir21a<tm1.1Mer>

http://metadb.riken.jp/0005596I129S1SvC57BL6FVBNMir21atm11MerMir21atm11MerMir21atm11Mer

increased susceptibility to type I hypersensitivity reaction_Mir21a<tm1.1Mer>/Mir21a<tm1.1Mer>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• microRNA 21a
  http://metadb.riken.jp/db/mgi_rdf/MGI:2676885

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Mir21a<tm1.1Mer>/Mir21a<tm1.1Mer>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Mir21a<tm1.1Mer>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * C57BL/6 * FVB/N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased susceptibility to type I hypersensitivity reaction
  http://purl.obolibrary.org/obo/MP_0005596

文献

http://purl.org/net/cito/citesAsAuthority

• Thomas X. Lu, et.al., MicroRNA-21 limits in vivo immune response-mediated activation of the IL-12/IFN-gamma pathway, Th1 polarization, and the severity of delayed-type hypersensitivity., Journal of immunology (Baltimore, Md. : 1950), 2011, 187
  http://rdf.ncbi.nlm.nih.gov/pubmed/21849676