decreased susceptibility to type I hypersensitivity reaction_Gna11<tm1Soff>/Gna11<tm1Soff>,Gnaq<tm2Soff>/Gnaq<tm2Soff>,Tg(Tek-cre/ERT2)1Soff/?

http://metadb.riken.jp/0005597I129P2OlaHsd129S7SvEvBrdFVBNGna11tm1SoffGna11tm1SoffGnaqtm2SoffGnaqtm2SoffTgTekcreERT21SoffGnaqtm2SoffGna11tm1SoffTgTekcreERT21Soff

decreased susceptibility to type I hypersensitivity reaction_Gna11<tm1Soff>/Gna11<tm1Soff>,Gnaq<tm2Soff>/Gnaq<tm2Soff>,Tg(Tek-cre/ERT2)1Soff/?

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• guanine nucleotide binding protein, alpha 11
  http://metadb.riken.jp/db/mgi_rdf/MGI:95766
• transgene insertion 1, Stefan Offermanns
  http://metadb.riken.jp/db/mgi_rdf/MGI:3837453
• guanine nucleotide binding protein, alpha q polypeptide
  http://metadb.riken.jp/db/mgi_rdf/MGI:95776

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Gna11<tm1Soff>/Gna11<tm1Soff>,Gnaq<tm2Soff>/Gnaq<tm2Soff>,Tg(Tek-cre/ERT2)1Soff/?

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Gnaq<tm2Soff>|Gna11<tm1Soff>|Tg(Tek-cre/ERT2)1Soff

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * 129S7/SvEvBrd * FVB/N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased susceptibility to type I hypersensitivity reaction
  http://purl.obolibrary.org/obo/MP_0005597

文献

http://purl.org/net/cito/citesAsAuthority

• Hanna. Korhonen, et.al., Anaphylactic shock depends on endothelial Gq/G11., The Journal of experimental medicine, 2009, 206
  http://rdf.ncbi.nlm.nih.gov/pubmed/19171764