decreased ventricle muscle contractility_Mtor<tm1.1Gcon>/Mtor<tm1.1Gcon>,A1cf<Tg(Myh6-cre/Esr1*)1Jmk>/0

http://metadb.riken.jp/0005598I129S1Sv129X1SvJC57BL6FVBNMtortm11GconMtortm11GconA1cfTgMyh6creEsr11Jmk0Mtortm11GconA1cfTgMyh6creEsr11Jmk

decreased ventricle muscle contractility_Mtor<tm1.1Gcon>/Mtor<tm1.1Gcon>,A1cf<Tg(Myh6-cre/Esr1*)1Jmk>/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• APOBEC1 complementation factor
  http://metadb.riken.jp/db/mgi_rdf/MGI:1917115
• mechanistic target of rapamycin (serine/threonine kinase)
  http://metadb.riken.jp/db/mgi_rdf/MGI:1928394

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Mtor<tm1.1Gcon>/Mtor<tm1.1Gcon>,A1cf<Tg(Myh6-cre/Esr1*)1Jmk>/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Mtor<tm1.1Gcon>|A1cf<Tg(Myh6-cre/Esr1*)1Jmk>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * FVB/N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased ventricle muscle contractility
  http://purl.obolibrary.org/obo/MP_0005598

文献

http://purl.org/net/cito/citesAsAuthority

• Denghong. Zhang, et.al., MTORC1 regulates cardiac function and myocyte survival through 4E-BP1 inhibition in mice., The Journal of clinical investigation, 2010, 120
  http://rdf.ncbi.nlm.nih.gov/pubmed/20644257