decreased ventricle muscle contractility_Atp1b1<tm1.1Akra>/Atp1b1<tm1.1Akra>,Myl2<tm1(cre)Krc>/Myl2<+>

http://metadb.riken.jp/0005598I129SSvEv129S4SvJaeAtp1b1tm11AkraAtp1b1tm11AkraMyl2tm1creKrcMyl2Myl2Atp1b1tm11AkraMyl2tm1creKrc

decreased ventricle muscle contractility_Atp1b1<tm1.1Akra>/Atp1b1<tm1.1Akra>,Myl2<tm1(cre)Krc>/Myl2<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• myosin, light polypeptide 2, regulatory, cardiac, slow
  http://metadb.riken.jp/db/mgi_rdf/MGI:97272
• ATPase, Na+/K+ transporting, beta 1 polypeptide
  http://metadb.riken.jp/db/mgi_rdf/MGI:88108

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Atp1b1<tm1.1Akra>/Atp1b1<tm1.1Akra>,Myl2<tm1(cre)Krc>/Myl2<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Myl2<+>|Atp1b1<tm1.1Akra>|Myl2<tm1(cre)Krc>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S/SvEv * 129S4/SvJae

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased ventricle muscle contractility
  http://purl.obolibrary.org/obo/MP_0005598

文献

http://purl.org/net/cito/citesAsAuthority

• Sonali P. Barwe, et.al., Dysfunction of ouabain-induced cardiac contractility in mice with heart-specific ablation of Na,K-ATPase beta1-subunit., Journal of molecular and cellular cardiology, 2009, 47
  http://rdf.ncbi.nlm.nih.gov/pubmed/19683723