increased cardiac muscle contractility_Atp1a1<tm2Ling>/Atp1a1<tm2Ling>,Atp1a2<tm3Ling>/Atp1a2<tm3Ling>

http://metadb.riken.jp/0005599I129S6SvEvTacBlackSwissAtp1a1tm2LingAtp1a1tm2LingAtp1a2tm3LingAtp1a2tm3LingAtp1a2tm3LingAtp1a1tm2Ling

increased cardiac muscle contractility_Atp1a1<tm2Ling>/Atp1a1<tm2Ling>,Atp1a2<tm3Ling>/Atp1a2<tm3Ling>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• ATPase, Na+/K+ transporting, alpha 1 polypeptide
  http://metadb.riken.jp/db/mgi_rdf/MGI:88105
• ATPase, Na+/K+ transporting, alpha 2 polypeptide
  http://metadb.riken.jp/db/mgi_rdf/MGI:88106

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Atp1a1<tm2Ling>/Atp1a1<tm2Ling>,Atp1a2<tm3Ling>/Atp1a2<tm3Ling>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Atp1a2<tm3Ling>|Atp1a1<tm2Ling>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S6/SvEvTac * Black Swiss

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased cardiac muscle contractility
  http://purl.obolibrary.org/obo/MP_0005599

文献

http://purl.org/net/cito/citesAsAuthority

• Iva. Dostanic, et.al., The alpha 1 isoform of Na,K-ATPase regulates cardiac contractility and functionally interacts and co-localizes with the Na/Ca exchanger in heart., The Journal of biological chemistry, 2004, 279
  http://rdf.ncbi.nlm.nih.gov/pubmed/15485817