increased bone mass_Gt(ROSA)26Sor<tm1(Vegfa*)Jhai>/Gt(ROSA)26Sor<+>,Kdr<tm1Wag>/Kdr<tm1Wag>,Tg(Col2a1-cre)1Bhr/0

http://metadb.riken.jp/0005605I129S1Sv129X1SvJC57BL6ICRSJLGtROSA26Sortm1VegfaJhaiGtROSA26SorKdrtm1WagKdrtm1WagTgCol2a1cre1Bhr0Kdrtm1WagTgCol2a1cre1BhrGtROSA26Sortm1VegfaJhaiGtROSA26Sor

increased bone mass_Gt(ROSA)26Sor<tm1(Vegfa*)Jhai>/Gt(ROSA)26Sor<+>,Kdr<tm1Wag>/Kdr<tm1Wag>,Tg(Col2a1-cre)1Bhr/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• kinase insert domain protein receptor
  http://metadb.riken.jp/db/mgi_rdf/MGI:96683
• gene trap ROSA 26, Philippe Soriano
  http://metadb.riken.jp/db/mgi_rdf/MGI:104735
• transgene insertion 1, Richard R Behringer
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176069

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Gt(ROSA)26Sor<tm1(Vegfa*)Jhai>/Gt(ROSA)26Sor<+>,Kdr<tm1Wag>/Kdr<tm1Wag>,Tg(Col2a1-cre)1Bhr/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Kdr<tm1Wag>|Tg(Col2a1-cre)1Bhr|Gt(ROSA)26Sor<tm1(Vegfa*)Jhai>|Gt(ROSA)26Sor<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * ICR * SJL

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased bone mass
  http://purl.obolibrary.org/obo/MP_0005605

文献

http://purl.org/net/cito/citesAsAuthority

• Christa. Maes, et.al., Increased skeletal VEGF enhances beta-catenin activity and results in excessively ossified bones., The EMBO journal, 2010, 29
  http://rdf.ncbi.nlm.nih.gov/pubmed/20010698