abnormal cell physiology_Ogg1<tm1Tno>/Ogg1<tm1Tno>,Tg(gptdelta)1Nmi/0

http://metadb.riken.jp/0005621I129S4SvJaeC57BL6JOgg1tm1TnoOgg1tm1TnoTggptdelta1Nmi0Ogg1tm1TnoTggptdelta1Nmi

abnormal cell physiology_Ogg1<tm1Tno>/Ogg1<tm1Tno>,Tg(gptdelta)1Nmi/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• 8-oxoguanine DNA-glycosylase 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:1097693
• transgene insertion 1, Takehito Nohmi
  http://metadb.riken.jp/db/mgi_rdf/MGI:3612990

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Ogg1<tm1Tno>/Ogg1<tm1Tno>,Tg(gptdelta)1Nmi/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Ogg1<tm1Tno>|Tg(gptdelta)1Nmi

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S4/SvJae * C57BL/6J

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal cell physiology
  http://purl.obolibrary.org/obo/MP_0005621

文献

http://purl.org/net/cito/citesAsAuthority

• Tsuyoshi. Arai, et.al., Cell proliferation in liver of Mmh/Ogg1-deficient mice enhances mutation frequency because of the presence of 8-hydroxyguanine in DNA., Cancer research, 2003, 63
  http://rdf.ncbi.nlm.nih.gov/pubmed/12874039
• O. Minowa, et.al., Mmh/Ogg1 gene inactivation results in accumulation of 8-hydroxyguanine in mice., Proceedings of the National Academy of Sciences of the United States of America, 2000, 97
  http://rdf.ncbi.nlm.nih.gov/pubmed/10725358