decreased dopamine level_Slc18a2<tm2Kmo>/Slc18a2<tm2Kmo>

http://metadb.riken.jp/0005643I129P2OlaHsdC57BL6Slc18a2tm2KmoSlc18a2tm2KmoSlc18a2tm2Kmo

decreased dopamine level_Slc18a2<tm2Kmo>/Slc18a2<tm2Kmo>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• solute carrier family 18 (vesicular monoamine), member 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:106677

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Slc18a2<tm2Kmo>/Slc18a2<tm2Kmo>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Slc18a2<tm2Kmo>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased dopamine level
  http://purl.obolibrary.org/obo/MP_0005643

文献

http://purl.org/net/cito/citesAsAuthority

• Tonya N. Taylor, et.al., Nonmotor symptoms of Parkinson's disease revealed in an animal model with reduced monoamine storage capacity., The Journal of neuroscience : the official journal of the Society for Neuroscience, 2009, 29
  http://rdf.ncbi.nlm.nih.gov/pubmed/19553450
• K A. Mooslehner, et.al., Mice with very low expression of the vesicular monoamine transporter 2 gene survive into adulthood: potential mouse model for parkinsonism., Molecular and cellular biology, 2001, 21
  http://rdf.ncbi.nlm.nih.gov/pubmed/11463816
• W Michael. Caudle, et.al., Reduced vesicular storage of dopamine causes progressive nigrostriatal neurodegeneration., The Journal of neuroscience : the official journal of the Society for Neuroscience, 2007, 27
  http://rdf.ncbi.nlm.nih.gov/pubmed/17652604