decreased dopamine level_Dbh<tm2(Th)Rpa>/Dbh<+>,Th<tm5Rpa>/Th<tm5Rpa>

http://metadb.riken.jp/0005643I129S4SvJaeSorC57BL6Dbhtm2ThRpaDbhThtm5RpaThtm5RpaThtm5RpaDbhDbhtm2ThRpa

decreased dopamine level_Dbh<tm2(Th)Rpa>/Dbh<+>,Th<tm5Rpa>/Th<tm5Rpa>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• dopamine beta hydroxylase
  http://metadb.riken.jp/db/mgi_rdf/MGI:94864
• tyrosine hydroxylase
  http://metadb.riken.jp/db/mgi_rdf/MGI:98735

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Dbh<tm2(Th)Rpa>/Dbh<+>,Th<tm5Rpa>/Th<tm5Rpa>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Th<tm5Rpa>|Dbh<+>|Dbh<tm2(Th)Rpa>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S4/SvJaeSor * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased dopamine level
  http://purl.obolibrary.org/obo/MP_0005643

文献

http://purl.org/net/cito/citesAsAuthority

• Thomas S. Hnasko, et.al., Cre recombinase-mediated restoration of nigrostriatal dopamine in dopamine-deficient mice reverses hypophagia and bradykinesia., Proceedings of the National Academy of Sciences of the United States of America, 2006, 103
  http://rdf.ncbi.nlm.nih.gov/pubmed/16723393