decreased dopamine level_Dbh<tm2(Th)Rpa>/Dbh<+>,Th<tm5Rpa>/Th<tm5Rpa>

http://metadb.riken.jp/0005643I129S4SvJaeSorDbhtm2ThRpaDbhThtm5RpaThtm5RpaThtm5RpaDbhDbhtm2ThRpa

decreased dopamine level_Dbh<tm2(Th)Rpa>/Dbh<+>,Th<tm5Rpa>/Th<tm5Rpa>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• dopamine beta hydroxylase
  http://metadb.riken.jp/db/mgi_rdf/MGI:94864
• tyrosine hydroxylase
  http://metadb.riken.jp/db/mgi_rdf/MGI:98735

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Dbh<tm2(Th)Rpa>/Dbh<+>,Th<tm5Rpa>/Th<tm5Rpa>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Th<tm5Rpa>|Dbh<+>|Dbh<tm2(Th)Rpa>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S4/SvJaeSor

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased dopamine level
  http://purl.obolibrary.org/obo/MP_0005643

文献

http://purl.org/net/cito/citesAsAuthority

• Benjamin B. Land, et.al., Activation of the kappa opioid receptor in the dorsal raphe nucleus mediates the aversive effects of stress and reinstates drug seeking., Proceedings of the National Academy of Sciences of the United States of America, 2009, 106
  http://rdf.ncbi.nlm.nih.gov/pubmed/19864633