increased susceptibility to diet-induced obesity_Prkaa1<tm1Sbj>/Prkaa1<+>,Prkaa2<tm1Vio>/Prkaa2<tm1Vio>

http://metadb.riken.jp/0005658I129S2SvPasFVBNPrkaa1tm1SbjPrkaa1Prkaa2tm1VioPrkaa2tm1VioPrkaa2tm1VioPrkaa1TgPomc1cre1GsbPrkaa1tm1Sbj

increased susceptibility to diet-induced obesity_Prkaa1<tm1Sbj>/Prkaa1<+>,Prkaa2<tm1Vio>/Prkaa2<tm1Vio>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• protein kinase, AMP-activated, alpha 1 catalytic subunit
  http://metadb.riken.jp/db/mgi_rdf/MGI:2145955
• protein kinase, AMP-activated, alpha 2 catalytic subunit
  http://metadb.riken.jp/db/mgi_rdf/MGI:1336173
• transgene insertion 1, Gregory S Barsh
  http://metadb.riken.jp/db/mgi_rdf/MGI:3576052

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Prkaa1<tm1Sbj>/Prkaa1<+>,Prkaa2<tm1Vio>/Prkaa2<tm1Vio>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Prkaa2<tm1Vio>|Prkaa1<+>|Tg(Pomc1-cre)1Gsb|Prkaa1<tm1Sbj>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S2/SvPas * FVB/N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased susceptibility to diet-induced obesity
  http://purl.obolibrary.org/obo/MP_0005658

文献

http://purl.org/net/cito/citesAsAuthority

• Marc. Claret, et.al., AMPK is essential for energy homeostasis regulation and glucose sensing by POMC and AgRP neurons., The Journal of clinical investigation, 2007, 117
  http://rdf.ncbi.nlm.nih.gov/pubmed/17671657