increased susceptibility to diet-induced obesity_Col1a1<tm1(tetO-Deptor)Dmsa>/Col1a1<+>,Gt(ROSA)26Sor<tm1(rtTA*M2)Jae>/?

http://metadb.riken.jp/0005658I129S4SvJaeC57BL6C57BL6JCol1a1tm1tetODeptorDmsaCol1a1GtROSA26Sortm1rtTAM2JaeCol1a1GtROSA26Sortm1rtTAM2JaeCol1a1tm1tetODeptorDmsa

increased susceptibility to diet-induced obesity_Col1a1<tm1(tetO-Deptor)Dmsa>/Col1a1<+>,Gt(ROSA)26Sor<tm1(rtTA*M2)Jae>/?

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• collagen, type I, alpha 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:88467
• gene trap ROSA 26, Philippe Soriano
  http://metadb.riken.jp/db/mgi_rdf/MGI:104735

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Col1a1<tm1(tetO-Deptor)Dmsa>/Col1a1<+>,Gt(ROSA)26Sor<tm1(rtTA*M2)Jae>/?

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Col1a1<+>|Gt(ROSA)26Sor<tm1(rtTA*M2)Jae>|Col1a1<tm1(tetO-Deptor)Dmsa>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S4/SvJae * C57BL/6 * C57BL/6J

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased susceptibility to diet-induced obesity
  http://purl.obolibrary.org/obo/MP_0005658

文献

http://purl.org/net/cito/citesAsAuthority

• Mathieu. Laplante, et.al., DEPTOR cell-autonomously promotes adipogenesis, and its expression is associated with obesity., Cell metabolism, 2012, 16
  http://rdf.ncbi.nlm.nih.gov/pubmed/22883231