decreased susceptibility to diet-induced obesity_Ccar2<tm1Dac>/Ccar2<tm1Dac>,Sirt1<tm1Ygu>/Sirt1<tm1Ygu>,Tg(SERPINA1-cre)1Arge/0

http://metadb.riken.jp/0005659I129129S1Sv129X1SvJC57BL6JCcar2tm1DacCcar2tm1DacSirt1tm1YguSirt1tm1YguTgSERPINA1cre1Arge0TgSERPINA1cre1ArgeCcar2tm1DacSirt1tm1Ygu

decreased susceptibility to diet-induced obesity_Ccar2<tm1Dac>/Ccar2<tm1Dac>,Sirt1<tm1Ygu>/Sirt1<tm1Ygu>,Tg(SERPINA1-cre)1Arge/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• cell cycle activator and apoptosis regulator 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:2444228
• sirtuin 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:2135607
• transgene insertion 1, Argiris Efstratiadis
  http://metadb.riken.jp/db/mgi_rdf/MGI:3821755

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Ccar2<tm1Dac>/Ccar2<tm1Dac>,Sirt1<tm1Ygu>/Sirt1<tm1Ygu>,Tg(SERPINA1-cre)1Arge/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(SERPINA1-cre)1Arge|Ccar2<tm1Dac>|Sirt1<tm1Ygu>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129 * 129S1/Sv * 129X1/SvJ * C57BL/6J

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased susceptibility to diet-induced obesity
  http://purl.obolibrary.org/obo/MP_0005659

文献

http://purl.org/net/cito/citesAsAuthority

• Li. Qiang, et.al., Hepatic SirT1-Dependent Gain of Function of Stearoyl-CoA Desaturase-1 Conveys Dysmetabolic and Tumor Progression Functions., Cell reports, 2015, 11
  http://rdf.ncbi.nlm.nih.gov/pubmed/26074075