decreased circulating leptin level_Ptpn1<tm2Bbk>/Ptpn1<tm2Bbk>,Tg(Nes-cre)1Kln/0

http://metadb.riken.jp/0005668I129S4SvJaeC57BL6SJLPtpn1tm2BbkPtpn1tm2BbkTgNescre1Kln0Ptpn1tm2BbkTgNescre1Kln

decreased circulating leptin level_Ptpn1<tm2Bbk>/Ptpn1<tm2Bbk>,Tg(Nes-cre)1Kln/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• protein tyrosine phosphatase, non-receptor type 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:97805
• transgene insertion 1, Rudiger Klein
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176172

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Ptpn1<tm2Bbk>/Ptpn1<tm2Bbk>,Tg(Nes-cre)1Kln/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Ptpn1<tm2Bbk>|Tg(Nes-cre)1Kln

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S4/SvJae * C57BL/6 * SJL

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased circulating leptin level
  http://purl.obolibrary.org/obo/MP_0005668

文献

http://purl.org/net/cito/citesAsAuthority

• Kim. Loh, et.al., Elevated hypothalamic TCPTP in obesity contributes to cellular leptin resistance., Cell metabolism, 2011, 14
  http://rdf.ncbi.nlm.nih.gov/pubmed/22000926