decreased circulating leptin level_Lep<tm1.1Gvcao>/Lep<tm1.1Gvcao>,Tg(Adipoq-cre)1Evdr/0

http://metadb.riken.jp/0005668I129S4SvJaeSorC57BL6JFVBNTacLeptm11GvcaoLeptm11GvcaoTgAdipoqcre1Evdr0Leptm11GvcaoTgAdipoqcre1Evdr

decreased circulating leptin level_Lep<tm1.1Gvcao>/Lep<tm1.1Gvcao>,Tg(Adipoq-cre)1Evdr/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• leptin
  http://metadb.riken.jp/db/mgi_rdf/MGI:104663
• transgene insertion 1, Evan Rosen
  http://metadb.riken.jp/db/mgi_rdf/MGI:4939582

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Lep<tm1.1Gvcao>/Lep<tm1.1Gvcao>,Tg(Adipoq-cre)1Evdr/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Lep<tm1.1Gvcao>|Tg(Adipoq-cre)1Evdr

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S4/SvJaeSor * C57BL/6J * FVB/NTac

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased circulating leptin level
  http://purl.obolibrary.org/obo/MP_0005668

文献

http://purl.org/net/cito/citesAsAuthority

• Angela K. Odle, et.al., Adipocyte versus pituitary leptin in the regulation of pituitary hormones: somatotropes develop normally in the absence of circulating leptin., Endocrinology, 2014, 155
  http://rdf.ncbi.nlm.nih.gov/pubmed/25116704