increased circulating leptin level_Irs2<tm1With>/Irs2<tm1With>,Tg(Nes-cre)1Kln/0

http://metadb.riken.jp/0005669I129S6SvEvTacC57BL6JIrs2tm1WithIrs2tm1WithTgNescre1Kln0TgNescre1KlnIrs2tm1With

increased circulating leptin level_Irs2<tm1With>/Irs2<tm1With>,Tg(Nes-cre)1Kln/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• insulin receptor substrate 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:109334
• transgene insertion 1, Rudiger Klein
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176172

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Irs2<tm1With>/Irs2<tm1With>,Tg(Nes-cre)1Kln/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Nes-cre)1Kln|Irs2<tm1With>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S6/SvEvTac * C57BL/6J

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased circulating leptin level
  http://purl.obolibrary.org/obo/MP_0005669

文献

http://purl.org/net/cito/citesAsAuthority

• Agharul I. Choudhury, et.al., The role of insulin receptor substrate 2 in hypothalamic and beta cell function., The Journal of clinical investigation, 2005, 115
  http://rdf.ncbi.nlm.nih.gov/pubmed/15841180