abnormal mitochondrion morphology_Fxn<tm2Mkn>/Fxn<tm2.1Mkn>,Tg(Ckmm-cre)1Lrsn/0

http://metadb.riken.jp/0006035I129C57BL6JFxntm2MknFxntm21MknTgCkmmcre1Lrsn0Fxntm21MknFxntm2MknTgCkmmcre1Lrsn

abnormal mitochondrion morphology_Fxn<tm2Mkn>/Fxn<tm2.1Mkn>,Tg(Ckmm-cre)1Lrsn/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 1, Nils-Goran Larsson
  http://metadb.riken.jp/db/mgi_rdf/MGI:2177172
• frataxin
  http://metadb.riken.jp/db/mgi_rdf/MGI:1096879

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Fxn<tm2Mkn>/Fxn<tm2.1Mkn>,Tg(Ckmm-cre)1Lrsn/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Fxn<tm2.1Mkn>|Fxn<tm2Mkn>|Tg(Ckmm-cre)1Lrsn

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129 * C57BL/6J

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal mitochondrion morphology
  http://purl.obolibrary.org/obo/MP_0006035

文献

http://purl.org/net/cito/citesAsAuthority

• Hervé. Seznec, et.al., Idebenone delays the onset of cardiac functional alteration without correction of Fe-S enzymes deficit in a mouse model for Friedreich ataxia., Human molecular genetics, 2004, 13
  http://rdf.ncbi.nlm.nih.gov/pubmed/15028670
• H. Puccio, et.al., Mouse models for Friedreich ataxia exhibit cardiomyopathy, sensory nerve defect and Fe-S enzyme deficiency followed by intramitochondrial iron deposits., Nature genetics, 2001, 27
  http://rdf.ncbi.nlm.nih.gov/pubmed/11175786