abnormal mitochondrion morphology_Twnk<tm1.1Lrsn>/Twnk<tm1.1Lrsn>,Tg(Ckmm-cre)5Khn/0

http://metadb.riken.jp/0006035IC57BL6FVBTwnktm11LrsnTwnktm11LrsnTgCkmmcre5Khn0TgCkmmcre5KhnTwnktm11Lrsn

abnormal mitochondrion morphology_Twnk<tm1.1Lrsn>/Twnk<tm1.1Lrsn>,Tg(Ckmm-cre)5Khn/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 5, C Ronald Kahn
  http://metadb.riken.jp/db/mgi_rdf/MGI:2182093
• twinkle mtDNA helicase
  http://metadb.riken.jp/db/mgi_rdf/MGI:2137410

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Twnk<tm1.1Lrsn>/Twnk<tm1.1Lrsn>,Tg(Ckmm-cre)5Khn/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Ckmm-cre)5Khn|Twnk<tm1.1Lrsn>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: C57BL/6 * FVB

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal mitochondrion morphology
  http://purl.obolibrary.org/obo/MP_0006035

文献

http://purl.org/net/cito/citesAsAuthority

• Dusanka. Milenkovic, et.al., TWINKLE is an essential mitochondrial helicase required for synthesis of nascent D-loop strands and complete mtDNA replication., Human molecular genetics, 2013, 22
  http://rdf.ncbi.nlm.nih.gov/pubmed/23393161