decreased apoptosis_Pacs2<Gt(OST426086)Lex>/Pacs2<Gt(OST426086)Lex>

http://metadb.riken.jp/0006043I129S5SvEvBrdNIHBlackSwissPacs2GtOST426086LexPacs2GtOST426086LexPacs2GtOST426086Lex

decreased apoptosis_Pacs2<Gt(OST426086)Lex>/Pacs2<Gt(OST426086)Lex>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• phosphofurin acidic cluster sorting protein 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:1924399

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Pacs2<Gt(OST426086)Lex>/Pacs2<Gt(OST426086)Lex>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Pacs2<Gt(OST426086)Lex>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S5/SvEvBrd * NIH Black Swiss

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased apoptosis
  http://purl.obolibrary.org/obo/MP_0006043

文献

http://purl.org/net/cito/citesAsAuthority

• Katelyn M. Atkins, et.al., HIV-1 Nef binds PACS-2 to assemble a multikinase cascade that triggers major histocompatibility complex class I (MHC-I) down-regulation: analysis using short interfering RNA and knock-out mice., The Journal of biological chemistry, 2008, 283
  http://rdf.ncbi.nlm.nih.gov/pubmed/18296443