mitral valve regurgitation_Bmpr1a<tm1Bhr>/Bmpr1a<tm2.1Bhr>,Tg(GATA6-cre)#Jbeb/0

http://metadb.riken.jp/0006045I129S7SvEvBrdC57BL6FVBBmpr1atm1BhrBmpr1atm21BhrTgGATA6creJbeb0Bmpr1atm1BhrTgGATA6creJbebBmpr1atm21Bhr

mitral valve regurgitation_Bmpr1a<tm1Bhr>/Bmpr1a<tm2.1Bhr>,Tg(GATA6-cre)#Jbeb/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• bone morphogenetic protein receptor, type 1A
  http://metadb.riken.jp/db/mgi_rdf/MGI:1338938
• transgene insertion #, John B E Burch
  http://metadb.riken.jp/db/mgi_rdf/MGI:3663688

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Bmpr1a<tm1Bhr>/Bmpr1a<tm2.1Bhr>,Tg(GATA6-cre)#Jbeb/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Bmpr1a<tm1Bhr>|Tg(GATA6-cre)#Jbeb|Bmpr1a<tm2.1Bhr>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S7/SvEvBrd * C57BL/6 * FVB

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• mitral valve regurgitation
  http://purl.obolibrary.org/obo/MP_0006045

文献

http://purl.org/net/cito/citesAsAuthority

• Vinciane. Gaussin, et.al., Alk3/Bmpr1a receptor is required for development of the atrioventricular canal into valves and annulus fibrosus., Circulation research, 2005, 97
  http://rdf.ncbi.nlm.nih.gov/pubmed/16037571