increased vascular endothelial cell number_Hif1a<tm3Rsjo>/Hif1a<tm3Rsjo>,Hprt<tm1(Pck1-cre)Vhh>/Y,Vhl<tm1Jae>/Vhl<tm1Jae>

http://metadb.riken.jp/0006056I129BALBcC57BL6Hif1atm3RsjoHif1atm3RsjoHprttm1Pck1creVhhYVhltm1JaeVhltm1JaeHif1atm3RsjoVhltm1JaeHprttm1Pck1creVhh

increased vascular endothelial cell number_Hif1a<tm3Rsjo>/Hif1a<tm3Rsjo>,Hprt<tm1(Pck1-cre)Vhh>/Y,Vhl<tm1Jae>/Vhl<tm1Jae>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• hypoxia inducible factor 1, alpha subunit
  http://metadb.riken.jp/db/mgi_rdf/MGI:106918
• hypoxanthine guanine phosphoribosyl transferase
  http://metadb.riken.jp/db/mgi_rdf/MGI:96217
• von Hippel-Lindau tumor suppressor
  http://metadb.riken.jp/db/mgi_rdf/MGI:103223

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Hif1a<tm3Rsjo>/Hif1a<tm3Rsjo>,Hprt<tm1(Pck1-cre)Vhh>/Y,Vhl<tm1Jae>/Vhl<tm1Jae>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Hif1a<tm3Rsjo>|Vhl<tm1Jae>|Hprt<tm1(Pck1-cre)Vhh>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129 * BALB/c * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased vascular endothelial cell number
  http://purl.obolibrary.org/obo/MP_0006056

文献

http://purl.org/net/cito/citesAsAuthority

• Erinn B. Rankin, et.al., Inactivation of the arylhydrocarbon receptor nuclear translocator (Arnt) suppresses von Hippel-Lindau disease-associated vascular tumors in mice., Molecular and cellular biology, 2005, 25
  http://rdf.ncbi.nlm.nih.gov/pubmed/15798202