increased fat cell size_Insr<tm1Khn>/Insr<tm1Khn>,Lepr<tm1.1Chua>/Lepr<tm1.1Chua>,Tg(Pomc1-cre)16Lowl/0

http://metadb.riken.jp/0006094I129129S4SvJae129S6SvEvTacC57BL6JFVBNInsrtm1KhnInsrtm1KhnLeprtm11ChuaLeprtm11ChuaTgPomc1cre16Lowl0Insrtm1KhnTgPomc1cre16LowlLeprtm11Chua

increased fat cell size_Insr<tm1Khn>/Insr<tm1Khn>,Lepr<tm1.1Chua>/Lepr<tm1.1Chua>,Tg(Pomc1-cre)16Lowl/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• leptin receptor
  http://metadb.riken.jp/db/mgi_rdf/MGI:104993
• insulin receptor
  http://metadb.riken.jp/db/mgi_rdf/MGI:96575
• transgene insertion 16, Bradford B Lowell
  http://metadb.riken.jp/db/mgi_rdf/MGI:3640615

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Insr<tm1Khn>/Insr<tm1Khn>,Lepr<tm1.1Chua>/Lepr<tm1.1Chua>,Tg(Pomc1-cre)16Lowl/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Insr<tm1Khn>|Tg(Pomc1-cre)16Lowl|Lepr<tm1.1Chua>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129 * 129S4/SvJae * 129S6/SvEvTac * C57BL/6J * FVB/N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased fat cell size
  http://purl.obolibrary.org/obo/MP_0006094

文献

http://purl.org/net/cito/citesAsAuthority

• Joseph S. Marino, et.al., Adipocyte dysfunction in a mouse model of polycystic ovary syndrome (PCOS): evidence of adipocyte hypertrophy and tissue-specific inflammation., PloS one, 2012, 7
  http://rdf.ncbi.nlm.nih.gov/pubmed/23119079