abnormal cardiac outflow tract development_Hand2<tm1Dsr>/Hand2<tm2.1Dsr>,Isl1<tm1(cre)Tmj>/Isl1<+>

http://metadb.riken.jp/0006126I129129S7SvEvBrd129X1SvJC57BL6Hand2tm1DsrHand2tm21DsrIsl1tm1creTmjIsl1Hand2tm21DsrIsl1Isl1tm1creTmjHand2tm1Dsr

abnormal cardiac outflow tract development_Hand2<tm1Dsr>/Hand2<tm2.1Dsr>,Isl1<tm1(cre)Tmj>/Isl1<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• heart and neural crest derivatives expressed 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:103580
• ISL1 transcription factor, LIM/homeodomain
  http://metadb.riken.jp/db/mgi_rdf/MGI:101791

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Hand2<tm1Dsr>/Hand2<tm2.1Dsr>,Isl1<tm1(cre)Tmj>/Isl1<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Hand2<tm2.1Dsr>|Isl1<+>|Isl1<tm1(cre)Tmj>|Hand2<tm1Dsr>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129 * 129S7/SvEvBrd * 129X1/SvJ * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal outflow tract development
  http://purl.obolibrary.org/obo/MP_0006126

文献

http://purl.org/net/cito/citesAsAuthority

• Takatoshi. Tsuchihashi, et.al., Hand2 function in second heart field progenitors is essential for cardiogenesis., Developmental biology, 2011, 351
  http://rdf.ncbi.nlm.nih.gov/pubmed/21185281