congestive heart failure_Adra1a<tm1Pcs>/Adra1a<tm1Pcs>,Adra1b<tm1Cta>/Adra1b<tm1Cta>

http://metadb.riken.jp/0006138I129P2OlaHsd129X1SvJC57BL6FVBNAdra1atm1PcsAdra1atm1PcsAdra1btm1CtaAdra1btm1CtaAdra1btm1CtaAdra1atm1Pcs

congestive heart failure_Adra1a<tm1Pcs>/Adra1a<tm1Pcs>,Adra1b<tm1Cta>/Adra1b<tm1Cta>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• adrenergic receptor, alpha 1a
  http://metadb.riken.jp/db/mgi_rdf/MGI:104773
• adrenergic receptor, alpha 1b
  http://metadb.riken.jp/db/mgi_rdf/MGI:104774

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Adra1a<tm1Pcs>/Adra1a<tm1Pcs>,Adra1b<tm1Cta>/Adra1b<tm1Cta>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Adra1b<tm1Cta>|Adra1a<tm1Pcs>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * 129X1/SvJ * C57BL/6 * FVB/N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• congestive heart failure
  http://purl.obolibrary.org/obo/MP_0006138

文献

http://purl.org/net/cito/citesAsAuthority

• Timothy D. O'Connell, et.al., The alpha(1A/C)- and alpha(1B)-adrenergic receptors are required for physiological cardiac hypertrophy in the double-knockout mouse., The Journal of clinical investigation, 2003, 111
  http://rdf.ncbi.nlm.nih.gov/pubmed/12782680