congestive heart failure_Npr1<tm1Kuhn>/Npr1<tm1Kuhn>,Tg(Myh6-cre)2182Mds/0

http://metadb.riken.jp/0006138I129S1Sv129X1SvJC57BL6FVBNNpr1tm1KuhnNpr1tm1KuhnTgMyh6cre2182Mds0Npr1tm1KuhnTgMyh6cre2182Mds

congestive heart failure_Npr1<tm1Kuhn>/Npr1<tm1Kuhn>,Tg(Myh6-cre)2182Mds/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 2182, Michael D Schneider
  http://metadb.riken.jp/db/mgi_rdf/MGI:2447636
• natriuretic peptide receptor 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:97371

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Npr1<tm1Kuhn>/Npr1<tm1Kuhn>,Tg(Myh6-cre)2182Mds/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Npr1<tm1Kuhn>|Tg(Myh6-cre)2182Mds

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * 129X1/SvJ * C57BL/6 * FVB/N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• congestive heart failure
  http://purl.obolibrary.org/obo/MP_0006138

文献

http://purl.org/net/cito/citesAsAuthority

• Rita. Holtwick, et.al., Pressure-independent cardiac hypertrophy in mice with cardiomyocyte-restricted inactivation of the atrial natriuretic peptide receptor guanylyl cyclase-A., The Journal of clinical investigation, 2003, 111
  http://rdf.ncbi.nlm.nih.gov/pubmed/12727932