increased systemic arterial systolic blood pressure_Edn1<tm1Ywa>/Edn1<tm1Ywa>,Tg(AQP2-cre)2Dek/0

http://metadb.riken.jp/0006144I129S6SvEvTacC57BL6CBAEdn1tm1YwaEdn1tm1YwaTgAQP2cre2Dek0Edn1tm1YwaTgAQP2cre2Dek

increased systemic arterial systolic blood pressure_Edn1<tm1Ywa>/Edn1<tm1Ywa>,Tg(AQP2-cre)2Dek/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• endothelin 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:95283
• transgene insertion 2, Donald E Kohan
  http://metadb.riken.jp/db/mgi_rdf/MGI:3054060

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Edn1<tm1Ywa>/Edn1<tm1Ywa>,Tg(AQP2-cre)2Dek/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Edn1<tm1Ywa>|Tg(AQP2-cre)2Dek

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S6/SvEvTac * C57BL/6 * CBA

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased systemic arterial systolic blood pressure
  http://purl.obolibrary.org/obo/MP_0006144

文献

http://purl.org/net/cito/citesAsAuthority

• Yuqiang. Ge, et.al., Collecting duct-specific knockout of the endothelin B receptor causes hypertension and sodium retention., American journal of physiology. Renal physiology, 2006, 291
  http://rdf.ncbi.nlm.nih.gov/pubmed/16868309