increased systemic arterial systolic blood pressure_Irs1<tm1Tka>/Irs1<tm1Tka>

http://metadb.riken.jp/0006144IC57BL6CBAIrs1tm1TkaIrs1tm1TkaIrs1tm1Tka

increased systemic arterial systolic blood pressure_Irs1<tm1Tka>/Irs1<tm1Tka>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• insulin receptor substrate 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:99454

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Irs1<tm1Tka>/Irs1<tm1Tka>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Irs1<tm1Tka>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: C57BL/6 * CBA

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased systemic arterial systolic blood pressure
  http://purl.obolibrary.org/obo/MP_0006144

文献

http://purl.org/net/cito/citesAsAuthority

• Tetsuya. Kubota, et.al., Lack of insulin receptor substrate-2 causes progressive neointima formation in response to vessel injury., Circulation, 2003, 107
  http://rdf.ncbi.nlm.nih.gov/pubmed/12810606
• H. Abe, et.al., Hypertension, hypertriglyceridemia, and impaired endothelium-dependent vascular relaxation in mice lacking insulin receptor substrate-1., The Journal of clinical investigation, 1998, 101
  http://rdf.ncbi.nlm.nih.gov/pubmed/9541510