impaired pupillary reflex_Gt(ROSA)26Sor<tm1(HBEGF)Awai>/Gt(ROSA)26Sor<+>,Opn4<tm1(cre)Sapa>/Opn4<+>

http://metadb.riken.jp/0006243I129SC57BL6GtROSA26Sortm1HBEGFAwaiGtROSA26SorOpn4tm1creSapaOpn4Opn4GtROSA26SorGtROSA26Sortm1HBEGFAwaiOpn4tm1creSapa

impaired pupillary reflex_Gt(ROSA)26Sor<tm1(HBEGF)Awai>/Gt(ROSA)26Sor<+>,Opn4<tm1(cre)Sapa>/Opn4<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• opsin 4 (melanopsin)
  http://metadb.riken.jp/db/mgi_rdf/MGI:1353425
• gene trap ROSA 26, Philippe Soriano
  http://metadb.riken.jp/db/mgi_rdf/MGI:104735

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Gt(ROSA)26Sor<tm1(HBEGF)Awai>/Gt(ROSA)26Sor<+>,Opn4<tm1(cre)Sapa>/Opn4<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Opn4<+>|Gt(ROSA)26Sor<+>|Gt(ROSA)26Sor<tm1(HBEGF)Awai>|Opn4<tm1(cre)Sapa>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• impaired pupillary reflex
  http://purl.obolibrary.org/obo/MP_0006243

文献

http://purl.org/net/cito/citesAsAuthority

• Megumi. Hatori, et.al., Inducible ablation of melanopsin-expressing retinal ganglion cells reveals their central role in non-image forming visual responses., PloS one, 2008, 3
  http://rdf.ncbi.nlm.nih.gov/pubmed/18545654