abnormal limb development_Fgf8<tm1.3Mrt>/Fgf8<tm1.4Mrt>,Tg(CAG-Bgeo,-Fgf4)1Mrt/?,Tg(Msx2-cre)5Rem/?

http://metadb.riken.jp/0006279I129P2OlaHsdFgf8tm13MrtFgf8tm14MrtTgCAGBgeoFgf41MrtTgMsx2cre5RemTgMsx2cre5RemFgf8tm14MrtFgf8tm13MrtTgCAGBgeoFgf41Mrt

abnormal limb development_Fgf8<tm1.3Mrt>/Fgf8<tm1.4Mrt>,Tg(CAG-Bgeo,-Fgf4)1Mrt/?,Tg(Msx2-cre)5Rem/?

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 1, Gail Martin
  http://metadb.riken.jp/db/mgi_rdf/MGI:3832272
• fibroblast growth factor 8
  http://metadb.riken.jp/db/mgi_rdf/MGI:99604
• transgene insertion 5, Robert E Maxson
  http://metadb.riken.jp/db/mgi_rdf/MGI:2159108

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Fgf8<tm1.3Mrt>/Fgf8<tm1.4Mrt>,Tg(CAG-Bgeo,-Fgf4)1Mrt/?,Tg(Msx2-cre)5Rem/?

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Msx2-cre)5Rem|Fgf8<tm1.4Mrt>|Fgf8<tm1.3Mrt>|Tg(CAG-Bgeo,-Fgf4)1Mrt

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal limb development
  http://purl.obolibrary.org/obo/MP_0006279

文献

http://purl.org/net/cito/citesAsAuthority

• Pengfei. Lu, et.al., Increasing Fgf4 expression in the mouse limb bud causes polysyndactyly and rescues the skeletal defects that result from loss of Fgf8 function., Development (Cambridge, England), 2006, 133
  http://rdf.ncbi.nlm.nih.gov/pubmed/16308330