increased medulloblastoma incidence_Ptch1<tm1Mps>/Ptch1<+>,Trp53<tm1Tyj>/Trp53<tm1Tyj>

http://metadb.riken.jp/0006283I129129S2SvPasC57BL6Ptch1tm1MpsPtch1Trp53tm1TyjTrp53tm1TyjTrp53tm1TyjPtch1Ptch1tm1Mps

increased medulloblastoma incidence_Ptch1<tm1Mps>/Ptch1<+>,Trp53<tm1Tyj>/Trp53<tm1Tyj>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transformation related protein 53
  http://metadb.riken.jp/db/mgi_rdf/MGI:98834
• patched 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:105373

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Ptch1<tm1Mps>/Ptch1<+>,Trp53<tm1Tyj>/Trp53<tm1Tyj>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Trp53<tm1Tyj>|Ptch1<+>|Ptch1<tm1Mps>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129 * 129S2/SvPas * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased medulloblastoma incidence
  http://purl.obolibrary.org/obo/MP_0006283

文献

http://purl.org/net/cito/citesAsAuthority

• Y. Lee, et.al., Loss of suppressor-of-fused function promotes tumorigenesis., Oncogene, 2007, 26
  http://rdf.ncbi.nlm.nih.gov/pubmed/17452975