increased medulloblastoma incidence_Trp53<tm1Brn>/Trp53<tm1Tyj>,Tg(Nes-cre)1Kln/0

http://metadb.riken.jp/0006283I129P2OlaHsd129S2SvPasC57BL6SJLTrp53tm1BrnTrp53tm1TyjTgNescre1Kln0TgNescre1KlnTrp53tm1BrnTrp53tm1Tyj

increased medulloblastoma incidence_Trp53<tm1Brn>/Trp53<tm1Tyj>,Tg(Nes-cre)1Kln/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 1, Rudiger Klein
  http://metadb.riken.jp/db/mgi_rdf/MGI:2176172
• transformation related protein 53
  http://metadb.riken.jp/db/mgi_rdf/MGI:98834

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Trp53<tm1Brn>/Trp53<tm1Tyj>,Tg(Nes-cre)1Kln/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Nes-cre)1Kln|Trp53<tm1Brn>|Trp53<tm1Tyj>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6 * SJL

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased medulloblastoma incidence
  http://purl.obolibrary.org/obo/MP_0006283

文献

http://purl.org/net/cito/citesAsAuthority

• Tamar. Uziel, et.al., The tumor suppressors Ink4c and p53 collaborate independently with Patched to suppress medulloblastoma formation., Genes & development, 2005, 19
  http://rdf.ncbi.nlm.nih.gov/pubmed/16260494