increased medulloblastoma incidence_Cdkn2c<tm1Bbd>/Cdkn2c<tm1Bbd>,Ptch1<tm1Mps>/Ptch1<+>

http://metadb.riken.jp/0006283I129S1Sv129S2SvPas129X1SvJCdkn2ctm1BbdCdkn2ctm1BbdPtch1tm1MpsPtch1Cdkn2ctm1BbdPtch1tm1MpsPtch1

increased medulloblastoma incidence_Cdkn2c<tm1Bbd>/Cdkn2c<tm1Bbd>,Ptch1<tm1Mps>/Ptch1<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4)
  http://metadb.riken.jp/db/mgi_rdf/MGI:105388
• patched 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:105373

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Cdkn2c<tm1Bbd>/Cdkn2c<tm1Bbd>,Ptch1<tm1Mps>/Ptch1<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Cdkn2c<tm1Bbd>|Ptch1<tm1Mps>|Ptch1<+>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * 129S2/SvPas * 129X1/SvJ

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased medulloblastoma incidence
  http://purl.obolibrary.org/obo/MP_0006283

文献

http://purl.org/net/cito/citesAsAuthority

• Tamar. Uziel, et.al., The tumor suppressors Ink4c and p53 collaborate independently with Patched to suppress medulloblastoma formation., Genes & development, 2005, 19
  http://rdf.ncbi.nlm.nih.gov/pubmed/16260494