increased medulloblastoma incidence_Trp53<tm1Elee>/Trp53<tm1Tyj>,Tg(GFAP-cre)25Mes/0

http://metadb.riken.jp/0006283I129S2SvPas129S4SvJaeFVBNTrp53tm1EleeTrp53tm1TyjTgGFAPcre25Mes0Trp53tm1EleeTrp53tm1TyjTgGFAPcre25Mes

increased medulloblastoma incidence_Trp53<tm1Elee>/Trp53<tm1Tyj>,Tg(GFAP-cre)25Mes/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transformation related protein 53
  http://metadb.riken.jp/db/mgi_rdf/MGI:98834
• transgene insertion 25, Albee Messing
  http://metadb.riken.jp/db/mgi_rdf/MGI:2179047

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Trp53<tm1Elee>/Trp53<tm1Tyj>,Tg(GFAP-cre)25Mes/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Trp53<tm1Elee>|Trp53<tm1Tyj>|Tg(GFAP-cre)25Mes

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S2/SvPas * 129S4/SvJae * FVB/N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased medulloblastoma incidence
  http://purl.obolibrary.org/obo/MP_0006283

文献

http://purl.org/net/cito/citesAsAuthority

• Yuan. Wang, et.al., Expression of mutant p53 proteins implicates a lineage relationship between neural stem cells and malignant astrocytic glioma in a murine model., Cancer cell, 2009, 15
  http://rdf.ncbi.nlm.nih.gov/pubmed/19477430