increased medulloblastoma incidence_Trp53<tm1Brd>/Trp53<tm1Brd>,Xrcc5<tm1Dbr>/Xrcc5<tm1Dbr>

http://metadb.riken.jp/0006283I129S7SvEvBrdC57BLTrp53tm1BrdTrp53tm1BrdXrcc5tm1DbrXrcc5tm1DbrXrcc5tm1DbrTrp53tm1Brd

increased medulloblastoma incidence_Trp53<tm1Brd>/Trp53<tm1Brd>,Xrcc5<tm1Dbr>/Xrcc5<tm1Dbr>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• X-ray repair complementing defective repair in Chinese hamster cells 5
  http://metadb.riken.jp/db/mgi_rdf/MGI:104517
• transformation related protein 53
  http://metadb.riken.jp/db/mgi_rdf/MGI:98834

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Trp53<tm1Brd>/Trp53<tm1Brd>,Xrcc5<tm1Dbr>/Xrcc5<tm1Dbr>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Xrcc5<tm1Dbr>|Trp53<tm1Brd>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S7/SvEvBrd * C57BL

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased medulloblastoma incidence
  http://purl.obolibrary.org/obo/MP_0006283

文献

http://purl.org/net/cito/citesAsAuthority

• V B. Holcomb, et.al., Ku80 and p53 suppress medulloblastoma that arise independent of Rag-1-induced DSBs., Oncogene, 2006, 25
  http://rdf.ncbi.nlm.nih.gov/pubmed/16751807