increased medulloblastoma incidence_Ptch1<tm1Bjw>/Ptch1<tm1Bjw>,Tg(Atoh1-cre)1Bfri/0

http://metadb.riken.jp/0006283I129T2SvEmsC57BL6CBAPtch1tm1BjwPtch1tm1BjwTgAtoh1cre1Bfri0TgAtoh1cre1BfriPtch1tm1Bjw

increased medulloblastoma incidence_Ptch1<tm1Bjw>/Ptch1<tm1Bjw>,Tg(Atoh1-cre)1Bfri/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 1, Bernd Fritzsch
  http://metadb.riken.jp/db/mgi_rdf/MGI:3775842
• patched 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:105373

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Ptch1<tm1Bjw>/Ptch1<tm1Bjw>,Tg(Atoh1-cre)1Bfri/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Atoh1-cre)1Bfri|Ptch1<tm1Bjw>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129T2/SvEms * C57BL/6 * CBA

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased medulloblastoma incidence
  http://purl.obolibrary.org/obo/MP_0006283

文献

http://purl.org/net/cito/citesAsAuthority

• Zeng-Jie. Yang, et.al., Medulloblastoma can be initiated by deletion of Patched in lineage-restricted progenitors or stem cells., Cancer cell, 2008, 14
  http://rdf.ncbi.nlm.nih.gov/pubmed/18691548