abnormal platelet activation_Lcp2<tm1Gak>/Lcp2<tm2Gak>,Tg(Pf4-icre)Q3Rsko/0,Gt(ROSA)26Sor<tm1(EYFP)Cos>/Gt(ROSA)26Sor<+>

http://metadb.riken.jp/0006298I129S1Sv129X1SvJC57BL6Lcp2tm1GakLcp2tm2GakTgPf4icreQ3Rsko0GtROSA26Sortm1EYFPCosGtROSA26SorLcp2tm1GakGtROSA26SorGtROSA26Sortm1EYFPCosLcp2tm2GakTgPf4icreQ3Rsko

abnormal platelet activation_Lcp2<tm1Gak>/Lcp2<tm2Gak>,Tg(Pf4-icre)Q3Rsko/0,Gt(ROSA)26Sor<tm1(EYFP)Cos>/Gt(ROSA)26Sor<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion Q3, Radek C Skoda
  http://metadb.riken.jp/db/mgi_rdf/MGI:3764699
• gene trap ROSA 26, Philippe Soriano
  http://metadb.riken.jp/db/mgi_rdf/MGI:104735
• lymphocyte cytosolic protein 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:1321402

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Lcp2<tm1Gak>/Lcp2<tm2Gak>,Tg(Pf4-icre)Q3Rsko/0,Gt(ROSA)26Sor<tm1(EYFP)Cos>/Gt(ROSA)26Sor<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Lcp2<tm1Gak>|Gt(ROSA)26Sor<+>|Gt(ROSA)26Sor<tm1(EYFP)Cos>|Lcp2<tm2Gak>|Tg(Pf4-icre)Q3Rsko

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * 129X1/SvJ * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal platelet activation
  http://purl.obolibrary.org/obo/MP_0006298

文献

http://purl.org/net/cito/citesAsAuthority

• Cara C. Bertozzi, et.al., Platelets regulate lymphatic vascular development through CLEC-2-SLP-76 signaling., Blood, 2010, 116
  http://rdf.ncbi.nlm.nih.gov/pubmed/20363774