decreased retinal ganglion cell number_Opn4<tm1.1(cre)Saha>/Opn4<tm1Yau>,Pou4f2<tm4Whk>/Pou4f2<+>

http://metadb.riken.jp/0006309I129SSvEvC57BL6Opn4tm11creSahaOpn4tm1YauPou4f2tm4WhkPou4f2Pou4f2tm4WhkOpn4tm11creSahaPou4f2Opn4tm1Yau

decreased retinal ganglion cell number_Opn4<tm1.1(cre)Saha>/Opn4<tm1Yau>,Pou4f2<tm4Whk>/Pou4f2<+>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• opsin 4 (melanopsin)
  http://metadb.riken.jp/db/mgi_rdf/MGI:1353425
• POU domain, class 4, transcription factor 2
  http://metadb.riken.jp/db/mgi_rdf/MGI:102524

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Opn4<tm1.1(cre)Saha>/Opn4<tm1Yau>,Pou4f2<tm4Whk>/Pou4f2<+>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Pou4f2<tm4Whk>|Opn4<tm1.1(cre)Saha>|Pou4f2<+>|Opn4<tm1Yau>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S/SvEv * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• decreased retinal ganglion cell number
  http://purl.obolibrary.org/obo/MP_0006309

文献

http://purl.org/net/cito/citesAsAuthority

• S-K. Chen, et.al., Photoentrainment and pupillary light reflex are mediated by distinct populations of ipRGCs., Nature, 2011, 476
  http://rdf.ncbi.nlm.nih.gov/pubmed/21765429