increased retinoblastoma incidence_Rb1<tm1Tyj>/Rb1<tm2Brn>,Rbl1<tm1Tyj>/Rbl1<tm1Tyj>,Trp53<tm1Brn>/Trp53<tm1Brn>,Tg(Chx10-EGFP/cre,-ALPP)2Clc/0

http://metadb.riken.jp/0006310I129P2OlaHsd129S2SvPasC57BL6SJLRb1tm1TyjRb1tm2BrnRbl1tm1TyjRbl1tm1TyjTrp53tm1BrnTrp53tm1BrnTgChx10EGFPcreALPP2Clc0Rbl1tm1TyjTrp53tm1BrnRb1tm1TyjTgChx10EGFPcreALPP2ClcRb1tm2Brn

increased retinoblastoma incidence_Rb1<tm1Tyj>/Rb1<tm2Brn>,Rbl1<tm1Tyj>/Rbl1<tm1Tyj>,Trp53<tm1Brn>/Trp53<tm1Brn>,Tg(Chx10-EGFP/cre,-ALPP)2Clc/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• RB transcriptional corepressor 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:97874
• transgene insertion 2, Constance L Cepko
  http://metadb.riken.jp/db/mgi_rdf/MGI:3052233
• retinoblastoma-like 1 (p107)
  http://metadb.riken.jp/db/mgi_rdf/MGI:103300
• transformation related protein 53
  http://metadb.riken.jp/db/mgi_rdf/MGI:98834

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Rb1<tm1Tyj>/Rb1<tm2Brn>,Rbl1<tm1Tyj>/Rbl1<tm1Tyj>,Trp53<tm1Brn>/Trp53<tm1Brn>,Tg(Chx10-EGFP/cre,-ALPP)2Clc/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Rbl1<tm1Tyj>|Trp53<tm1Brn>|Rb1<tm1Tyj>|Tg(Chx10-EGFP/cre,-ALPP)2Clc|Rb1<tm2Brn>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * 129S2/SvPas * C57BL/6 * SJL

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased retinoblastoma incidence
  http://purl.obolibrary.org/obo/MP_0006310

文献

http://purl.org/net/cito/citesAsAuthority

• Dianna A. Johnson, et.al., Neuronal differentiation and synaptogenesis in retinoblastoma., Cancer research, 2007, 67
  http://rdf.ncbi.nlm.nih.gov/pubmed/17363591