abnormal lung epithelium morphology_Eya1<tm1Rilm>/Eya1<tm1Rilm>,Notch1<tm2Rko>/Notch1<tm2Rko>,Tg(SFTPC-rtTA)5Jaw/?,Tg(tetO-cre)1Jaw/?

http://metadb.riken.jp/0006382I129129S1Sv129X1SvJC57BL6Eya1tm1RilmEya1tm1RilmNotch1tm2RkoNotch1tm2RkoTgSFTPCrtTA5JawTgtetOcre1JawTgtetOcre1JawTgSFTPCrtTA5JawEya1tm1RilmNotch1tm2Rko

abnormal lung epithelium morphology_Eya1<tm1Rilm>/Eya1<tm1Rilm>,Notch1<tm2Rko>/Notch1<tm2Rko>,Tg(SFTPC-rtTA)5Jaw/?,Tg(tetO-cre)1Jaw/?

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 5, Jeffrey A Whitsett
  http://metadb.riken.jp/db/mgi_rdf/MGI:2679530
• notch 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:97363
• transgene insertion 1, Jeffrey A Whitsett
  http://metadb.riken.jp/db/mgi_rdf/MGI:3028584
• EYA transcriptional coactivator and phosphatase 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:109344

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Eya1<tm1Rilm>/Eya1<tm1Rilm>,Notch1<tm2Rko>/Notch1<tm2Rko>,Tg(SFTPC-rtTA)5Jaw/?,Tg(tetO-cre)1Jaw/?

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(tetO-cre)1Jaw|Tg(SFTPC-rtTA)5Jaw|Eya1<tm1Rilm>|Notch1<tm2Rko>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129 * 129S1/Sv * 129X1/SvJ * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• abnormal lung epithelium morphology
  http://purl.obolibrary.org/obo/MP_0006382

文献

http://purl.org/net/cito/citesAsAuthority

• Ahmed H K. El-Hashash, et.al., Eya1 controls cell polarity, spindle orientation, cell fate and Notch signaling in distal embryonic lung epithelium., Development (Cambridge, England), 2011, 138
  http://rdf.ncbi.nlm.nih.gov/pubmed/21385765