increased T cell apoptosis_Stat3<tm2Aki>/Stat3<tm2Aki>,Tg(Lck-cre)1Jtak/0

http://metadb.riken.jp/0006413I129P2OlaHsdStat3tm2AkiStat3tm2AkiTgLckcre1Jtak0Stat3tm2AkiTgLckcre1Jtak

increased T cell apoptosis_Stat3<tm2Aki>/Stat3<tm2Aki>,Tg(Lck-cre)1Jtak/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• signal transducer and activator of transcription 3
  http://metadb.riken.jp/db/mgi_rdf/MGI:103038
• transgene insertion 1, Junji Takeda
  http://metadb.riken.jp/db/mgi_rdf/MGI:3655253

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Stat3<tm2Aki>/Stat3<tm2Aki>,Tg(Lck-cre)1Jtak/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Stat3<tm2Aki>|Tg(Lck-cre)1Jtak

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased T cell apoptosis
  http://purl.obolibrary.org/obo/MP_0006413

文献

http://purl.org/net/cito/citesAsAuthority

• K. Takeda, et.al., Stat3 activation is responsible for IL-6-dependent T cell proliferation through preventing apoptosis: generation and characterization of T cell-specific Stat3-deficient mice., Journal of immunology (Baltimore, Md. : 1950), 1998, 161
  http://rdf.ncbi.nlm.nih.gov/pubmed/9794394