increased T cell apoptosis_Mcl1<tm1Ywh>/Mcl1<tm1Ywh>,Tg(Cd4-cre)1Cwi/0

http://metadb.riken.jp/0006413I129S6SvEvTacC57BL6DBA2Mcl1tm1YwhMcl1tm1YwhTgCd4cre1Cwi0TgCd4cre1CwiMcl1tm1Ywh

increased T cell apoptosis_Mcl1<tm1Ywh>/Mcl1<tm1Ywh>,Tg(Cd4-cre)1Cwi/0

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transgene insertion 1, Christopher B Wilson
  http://metadb.riken.jp/db/mgi_rdf/MGI:2448688
• myeloid cell leukemia sequence 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:101769

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Mcl1<tm1Ywh>/Mcl1<tm1Ywh>,Tg(Cd4-cre)1Cwi/0

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Tg(Cd4-cre)1Cwi|Mcl1<tm1Ywh>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S6/SvEvTac * C57BL/6 * DBA/2

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased T cell apoptosis
  http://purl.obolibrary.org/obo/MP_0006413

文献

http://purl.org/net/cito/citesAsAuthority

• Ivan. Dzhagalov, et.al., The anti-apoptotic Bcl-2 family member Mcl-1 promotes T lymphocyte survival at multiple stages., Journal of immunology (Baltimore, Md. : 1950), 2008, 181
  http://rdf.ncbi.nlm.nih.gov/pubmed/18566418