increased ovary tumor incidence_Brca2<tm1Brn>/Brca2<tm1Brn>,Tg(Krt18-EGFP,-TAg121)36Ysng/0,Trp53<tm1Brn>/Trp53<tm2Tyj>

http://metadb.riken.jp/0008000I129P2OlaHsd129S4SvJaeC57BL6DBA2FVBNBrca2tm1BrnBrca2tm1BrnTgKrt18EGFPTAg12136Ysng0Trp53tm1BrnTrp53tm2TyjTrp53tm2TyjBrca2tm1BrnTgKrt18EGFPTAg12136YsngTrp53tm1Brn

increased ovary tumor incidence_Brca2<tm1Brn>/Brca2<tm1Brn>,Tg(Krt18-EGFP,-TAg121)36Ysng/0,Trp53<tm1Brn>/Trp53<tm2Tyj>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• breast cancer 2, early onset
  http://metadb.riken.jp/db/mgi_rdf/MGI:109337
• transformation related protein 53
  http://metadb.riken.jp/db/mgi_rdf/MGI:98834
• transgene insertion 36, Yurong Song
  http://metadb.riken.jp/db/mgi_rdf/MGI:5449062

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Brca2<tm1Brn>/Brca2<tm1Brn>,Tg(Krt18-EGFP,-TAg121)36Ysng/0,Trp53<tm1Brn>/Trp53<tm2Tyj>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Trp53<tm2Tyj>|Brca2<tm1Brn>|Tg(Krt18-EGFP,-TAg121)36Ysng|Trp53<tm1Brn>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * 129S4/SvJae * C57BL/6 * DBA/2 * FVB/N

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased ovary tumor incidence
  http://purl.obolibrary.org/obo/MP_0008000

文献

http://purl.org/net/cito/citesAsAuthority

• Ludmila. Szabova, et.al., Perturbation of Rb, p53, and Brca1 or Brca2 cooperate in inducing metastatic serous epithelial ovarian cancer., Cancer research, 2012, 72
  http://rdf.ncbi.nlm.nih.gov/pubmed/22617326