increased ovary tumor incidence_Amhr2<tm3(cre)Bhr>/Amhr2<+>,Smad1<tm2Rob>/Smad1<tm2.1Rob>,Smad5<tm1Huy>/Smad5<tm1Huy>

http://metadb.riken.jp/0008000I129P2OlaHsd129SSvEvC57BL6Amhr2tm3creBhrAmhr2Smad1tm2RobSmad1tm21RobSmad5tm1HuySmad5tm1HuySmad5tm1HuyAmhr2Smad1tm21RobSmad1tm2RobAmhr2tm3creBhr

increased ovary tumor incidence_Amhr2<tm3(cre)Bhr>/Amhr2<+>,Smad1<tm2Rob>/Smad1<tm2.1Rob>,Smad5<tm1Huy>/Smad5<tm1Huy>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• anti-Mullerian hormone type 2 receptor
  http://metadb.riken.jp/db/mgi_rdf/MGI:105062
• SMAD family member 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:109452
• SMAD family member 5
  http://metadb.riken.jp/db/mgi_rdf/MGI:1328787

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Amhr2<tm3(cre)Bhr>/Amhr2<+>,Smad1<tm2Rob>/Smad1<tm2.1Rob>,Smad5<tm1Huy>/Smad5<tm1Huy>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Smad5<tm1Huy>|Amhr2<+>|Smad1<tm2.1Rob>|Smad1<tm2Rob>|Amhr2<tm3(cre)Bhr>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd * 129S/SvEv * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased ovary tumor incidence
  http://purl.obolibrary.org/obo/MP_0008000

文献

http://purl.org/net/cito/citesAsAuthority

• Stephanie A. Pangas, et.al., Conditional deletion of Smad1 and Smad5 in somatic cells of male and female gonads leads to metastatic tumor development in mice., Molecular and cellular biology, 2008, 28
  http://rdf.ncbi.nlm.nih.gov/pubmed/17967875