increased ovary tumor incidence_Rb1<tm2Brn>/Rb1<tm2Brn>,Trp53<tm1Brn>/Trp53<tm1Brn>

http://metadb.riken.jp/0008000I129P2OlaHsdRb1tm2BrnRb1tm2BrnTrp53tm1BrnTrp53tm1BrnTrp53tm1BrnRb1tm2Brn

increased ovary tumor incidence_Rb1<tm2Brn>/Rb1<tm2Brn>,Trp53<tm1Brn>/Trp53<tm1Brn>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transformation related protein 53
  http://metadb.riken.jp/db/mgi_rdf/MGI:98834
• RB transcriptional corepressor 1
  http://metadb.riken.jp/db/mgi_rdf/MGI:97874

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Rb1<tm2Brn>/Rb1<tm2Brn>,Trp53<tm1Brn>/Trp53<tm1Brn>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Trp53<tm1Brn>|Rb1<tm2Brn>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129P2/OlaHsd

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased ovary tumor incidence
  http://purl.obolibrary.org/obo/MP_0008000

文献

http://purl.org/net/cito/citesAsAuthority

• Andrea. Flesken-Nikitin, et.al., Induction of carcinogenesis by concurrent inactivation of p53 and Rb1 in the mouse ovarian surface epithelium., Cancer research, 2003, 63
  http://rdf.ncbi.nlm.nih.gov/pubmed/12839925