increased ovary tumor incidence_Inha<tm1Bay>/Inha<tm1Bay>,Smad3<tm1Par>/Smad3<tm1Par>

http://metadb.riken.jp/0008000I129S1Sv129S7SvEvBr129X1SvC57BL6Inhatm1BayInhatm1BaySmad3tm1ParSmad3tm1ParSmad3tm1ParInhatm1Bay

increased ovary tumor incidence_Inha<tm1Bay>/Inha<tm1Bay>,Smad3<tm1Par>/Smad3<tm1Par>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• SMAD family member 3
  http://metadb.riken.jp/db/mgi_rdf/MGI:1201674
• inhibin alpha
  http://metadb.riken.jp/db/mgi_rdf/MGI:96569

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Inha<tm1Bay>/Inha<tm1Bay>,Smad3<tm1Par>/Smad3<tm1Par>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Smad3<tm1Par>|Inha<tm1Bay>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• involves: 129S1/Sv * 129S7/SvEvBr * 129X1/Sv * C57BL/6

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• increased ovary tumor incidence
  http://purl.obolibrary.org/obo/MP_0008000

文献

http://purl.org/net/cito/citesAsAuthority

• Brendan D. Looyenga, et.al., Genetic removal of Smad3 from inhibin-null mice attenuates tumor progression by uncoupling extracellular mitogenic signals from the cell cycle machinery., Molecular endocrinology (Baltimore, Md.), 2007, 21
  http://rdf.ncbi.nlm.nih.gov/pubmed/17652186