early cellular replicative senescence_Trp53<tm1Tyj>/Trp53<tm1Tyj>,Trp63<tm1.1Elrf>/Trp63<tm1.1Elrf>

http://metadb.riken.jp/0008008EI129S2SvPasC57BL6FVBNorI129S2SvPas129S4SvJae129S6SvEvTacC57BL6Trp53tm1TyjTrp53tm1TyjTrp63tm11ElrfTrp63tm11ElrfTrp53tm1TyjTrp63tm11Elrf

early cellular replicative senescence_Trp53<tm1Tyj>/Trp53<tm1Tyj>,Trp63<tm1.1Elrf>/Trp63<tm1.1Elrf>

表現型アノテーション

MGI marker

http://metadb.riken.jp/db/mgi_rdf/variant_of

• transformation related protein 63
  http://metadb.riken.jp/db/mgi_rdf/MGI:1330810
• transformation related protein 53
  http://metadb.riken.jp/db/mgi_rdf/MGI:98834

遺伝子型

http://metadb.riken.jp/db/mgi_rdf/allele_composition

• Trp53<tm1Tyj>/Trp53<tm1Tyj>,Trp63<tm1.1Elrf>/Trp63<tm1.1Elrf>

アレルシンボル

http://metadb.riken.jp/db/mgi_rdf/allele_symbol

• Trp53<tm1Tyj>|Trp63<tm1.1Elrf>

遺伝的背景

http://metadb.riken.jp/db/mgi_rdf/genetic_background

• either: (involves: 129S2/SvPas * C57BL/6 * FVB/N) or (involves: 129S2/SvPas * 129S4/SvJae * 129S6/SvEvTac * C57BL/6)

MP annotation

http://metadb.riken.jp/db/bioresource_schema/brs_indicatesPhenotype

• early cellular replicative senescence
  http://purl.obolibrary.org/obo/MP_0008008

文献

http://purl.org/net/cito/citesAsAuthority

• Xiaohua. Su, et.al., TAp63 prevents premature aging by promoting adult stem cell maintenance., Cell stem cell, 2009, 5
  http://rdf.ncbi.nlm.nih.gov/pubmed/19570515